Last edited by Arashikus
Saturday, August 8, 2020 | History

5 edition of Methods and Mechanisms for Producing Ions from Large Molecules (NATO Science Series: B:) found in the catalog.

Methods and Mechanisms for Producing Ions from Large Molecules (NATO Science Series: B:)

  • 110 Want to read
  • 8 Currently reading

Published by Springer .
Written in English

    Subjects:
  • Nuclear structure physics,
  • Molecular Physics,
  • Science,
  • Science/Mathematics,
  • Science / Nuclear Physics,
  • Nuclear Physics,
  • Biomolecules,
  • Congresses,
  • Ionization,
  • Mass spectrometry,
  • Particle beams

  • Edition Notes

    ContributionsK.G. Standing (Editor), W. Ens (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages344
    ID Numbers
    Open LibraryOL10324475M
    ISBN 100306440172
    ISBN 109780306440175

    Endocytosis. Endocytosis is a type of active transport that moves particles, such as large molecules, parts of cells, and even whole cells, into a cell. There are different variations of endocytosis, but all share a common characteristic: the plasma membrane of the cell invaginates, forming a . However, output of analyte ions can be low and post-ionization methods such as inductively coupled plasma (ICP) are needed. LDI utilizes lower intensity (I) laser pulses, I ≤ 10 MW/cm 2; metabolites and relatively large intact molecules, like peptides and some proteins, can be desorbed and ionized. An increase in energy leads to more.

      MECHANISMS • Ionophores: special carrier molecules that wrap around metal ions so they can pass through the membrane by diffusion • Ion Channels: large, membrane-spanning molecule that form a hydrophilic path for diffusion • Ion Pumps: molecules using energy to transport ions in one direction through a membrane Dissolved in the cytosol are a variety of ions and molecules varying from the small to the large; among the latter, proteins and carbohydrates make up the "solid" portion of the gel structure. → Embedded within the cytosol is the filament-like cytoskeleton which controls the overall shape of the cell and holds the organelles in place.

    molecules impart charge to the analyte molecules via charge transfer reactions or molecular association. Both ESI and APCI are termed “soft” ionisation methods. This means that in the process of producing ions there is negligible energy transferred to the ion. As a consequence the ion formed does not fragment to small mass ions.   Water is a critical component of many chemical processes, in fields as diverse as biology and geology. Water in chemical, biological, and other systems frequently occurs in very crowded situations: the confined water must interact with a variety of interfaces and molecular groups, often on a characteristic length scale of nanometers. Water’s behavior in diverse environments is an important.


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Methods and Mechanisms for Producing Ions from Large Molecules (NATO Science Series: B:) Download PDF EPUB FB2

A NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules was held at Minaki Lodge, Minaki, Ontario, Canada, from 24 to 28 June The workshop was hosted by the time-of-flight group of the Department of Physics at the University of Manitoba, and was attended by 64 invited participants from around.

Get this from a library. Methods and Mechanisms for Producing Ions from Large Molecules. [K G Standing; Werner Ens] -- A NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules was held at Minaki Lodge, Minaki, Ontario, Canada, from 24 to 28 June The workshop was hosted.

Buy Methods and Mechanisms for Producing Ions from Large Molecules (Nato Science Series B:) Softcover reprint of the original 1st ed. by Kenneth Standing, W. Ens (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders.

ISBN: OCLC Number: Notes: "Proceedings of a NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules, held June, at Minaki Lodge, Minaki, Canada"--Title page verso. BOOK REVIEWS 1 Am Sm Mass Spectrom7~” Methods and Mechanisms for Producing Ions from Large Molecules Edited by K.

Standing and Werner Ens Nato Advanced Study Institute Series B: Physics, Vol. Plenum Press, Spring Street, New York, NY, $ Methods and mechanisms for producing ions from large molecules / ed. by K.G. Standing and Werner Ens Date: Editeur / Publisher: New York [etc.]: Plenum Press, cop. Vertes A.

() Laser Desorption of Large Molecules: Mechanisms and Models. In: Standing K.G., Ens W. (eds) Methods and Mechanisms for Producing Ions from Large Molecules.

NATO ASI Series (Series B: Physics), vol Ejection from the solid state of large, thermally-labile organic molecules occurs due to the energy deposited by fast heavy ions or by laser-pulse excitation of a matrix material.

Laser-pulse-induced ejection is described using the ‘pressure pulse’ model developed for heavy-ion-induced ejection and its relationship to sublimation is considered.

The desorption of large thermolabile molecules under heavy ion bombardment, discovered by Macfarlane et al [1] inis the basis for a new trend in mass spectrometry.

This phenomenon has been studied experimentally rather well [2]. In ref. [3] the shock wave mechanism of biomolecule sputtering has been developed. The ion flux was caletdated from the colli- sion frequency of the ions with the bilayer surface, and the total area of pores in the bilayer which are large enough and deep enough to allow an ion to cross the bilayer, Given these assumptions, the ionic permeability Pi is (-) Pi = R~,A~.k'~--'-~ si + ~ exp(-ktsi/RT) Xexp(-kzd/RT) (14) where Di.

In chemistry, ionization often occurs in a liquid example, neutral molecules of hydrogen chloride gas, HCl, react with similarly polar water molecules, H 2 O, to produce positive hydronium ions, H 3 O +, and negative chloride ions, Cl-; at the surface of a piece of metallic zinc in contact with an acidic solution, zinc atoms, Zn, lose electrons to hydrogen ions and become.

Chemical ionization (CI) CI uses a reagent ion to react with the analyte molecules to form ions by either a proton or hydride transfer: MH + C 2 H 5 +--> MH 2 + + C 2 H 4. MH + C 2 H 5 +--> M + + C 2 H 6.

The reagent ions are produced by introducing a large excess of methane (relative to the analyte) into an electron impact (EI) ion source. Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated series of events that are amplified by endogenous signaling and culminating in oxidative damage to DNA, lipids, proteins, and many metabolites.

Despite the global impact of IR, the molecular mechanisms underlying tissue damage reveal that many biomolecules are chemoselectively modified by IR. We have performed ion beam collision experiments using multiply charged tantalum ions and observed EUV (extreme ultra-violet) emission spectra in collisions of ions with molecular targets, N 2 and O UTAs (un-resolved transition arrays) from multiply charged Ta ions were observed, and the mean wavelengths of the UTAs shifted and became shorter at higher charge statea of Ta ions.

Fig. 4 shows that one Ar + ion can break uridine molecules, nearly molecules/eV. For MeV C ions, this value is molecules/eV, about five times more. This difference comes from the different interaction mechanisms of the nuclear energy loss and electronic energy loss processes.

We point out a laser cooling method for atoms, molecules, or ions at low saturation and large detuning from the particles' resonances. The moving particle modifies the field inside a cavity with a.

Initially, it is hard to imagine a mechanism that would exclude a molecule as small as water from a protein surface without affecting the access of the ligand itself.

Because of the strong tendency of water molecules to form water–water hydrogen bonds, however, water molecules exist in a large hydrogen-bonded network (see Panelpp. In general, for small molecules the parent ion is the dominant ion at all impact energies, although there are exceptions, such as CCl 4 and CF 4 which have no stable parent ions.

Conversely, for large molecules the relative parent-ion abundance usually decreases with increasing molecular mass and increasing incident energy.

An ion (/ ˈ aɪ ɒ n,-ən /) is an atom or molecule that has a net electrical the charge of the electron (considered negative by convention) is equal and opposite to that of the proton (considered positive by convention), the net charge of an ion is non-zero due to its total number of electrons being unequal to its total number of protons.A cation is a positively charged ion.

For many years, receptors on neurons have been considered to fall into two categories based on their structure and function. One forms a channel (ionic) where ions flow with a mechanism based on electrical charge.

The other large class of receptors are molecules that trigger cascades of other molecules just below the membrane. Non-viral methods present certain advantages over viral methods, with simple large scale production and low host immunogenicity being just two.

Previously, low levels of transfection and expression of the gene held non-viral methods at a disadvantage; however, recent advances in vector technology have yielded molecules and techniques with. Both MCM and SBA could easily accommodate large molecules such as proteins and enzymes, which explains their huge popularity.

Other silica-based mesoporous materials have been described, such as Michigan State University (MSU)-1 [ 75 ] and Mesostructured Cellular Foam (MCF) [ 76 ], although they have drawn no attention as tools for.In conclusion we elucidated the atomic mechanisms of ZnO nanoparticle stabilization by charged surfactants and its interplay with Na + counterions from the embedding ethanolic solution.

A large fraction of the sodium ions tends to bind to the nanoparticle-surfactant molecules system, and may hence be considered as surfactants as well.